Diabetes and Respiratory tract infections

Respiratory infections are very common infections in kids as well as adults. We  know that respiratory tract infections are usually due to lower immunity response. Type 1 diabetes increases the tendency for both chronic and acute infections by weakening the immune mechanisms. The risk is specifically increased for respiratory tract infections, along with other infections have also been associated with diabetes. Study was conducted where investigation was carried out whether viral respiratory tract infections in children with type 1 diabetes might impose an additional burden on the arterial endothelial function or not.

As per the study, Upper-respiratory infections in early childhood and especially in the first year of life is associated with an increased risk for type 1 Diabetes Mellitus.

Diabetes and respiratory tract infections.

Epidemiology:

The incidence of diabetes mellitus is increasing rapidly in India as well as abroad. In addition to well-known other complications, diabetes increases the risk for hospitalization and death from severe acute respiratory infection (SARI) and influenza, pneumonia and tuberculosis. Male are more affected than females. Older groups are more prone to respiratory tract infections than younger groups.

Pathophysiology:

Diabetes increases the susceptibility to get different kinds of respiratory infections, which is usually identified as an solo risk factor for developing lower respiratory tract infections. Pulmonary infections caused by staphylococcus aureus, Mycobacterium tuberculosis, gram-negative bacteria and fungi may occur with an increased frequency, whereas infections due to influenza virus or Streptococcus pneumonia may be associated with increased mortality and morbidity.

During lung infection, there are changes in the ciliary epithelial lining. Increased susceptibility to pneumococcal infection by individuals with diabetes is due to reduced defense capability of antibodies to protein antigens.  The incidence of tuberculosis in diabetic individuals is 5-6 times greater than among the non-diabetic population. It is observed that the malfunction of monocytes in patients with diabetes may contribute to the increased susceptibility to tuberculosis with a worse prognosis. Hospitalization of patients with diabetes due to influenza virus or flu-like infections is up to 7 times more likely to occur compared to healthy individuals, also diabetic patients are more likely to be hospitalized due to infection complications.

Signs and Symptoms:

  • Breathlessness
  • Wet Cough and cold, running nose in case of upper respiratory infections.
  • Fever
  • Loss of weight
  • Weakness
  • Bodyache, headache
  • Itching of the body
  • Thirst for sips of water

Investigation and Diagnosis:

  • CBC
  • ESR
  • X ray chest PA view
  • Blood sugar levels both fasting and Post pariandal
  • CT scan chest for extent of pneumonia
  • Chest pain
  • Sputum examination for bacteria
  • Mantoux test to rule out tuberculosis.

Management:

Immunization with influenza and anti-pneumococcal vaccines is the usual mode of treatment recommended to reduce hospitalizations, medical expenses and deaths. Also Diabetes should be monitored on regular basis. Antibiotics should be administered along with antitussives for upper respiratory tract infections like cold and cough with throat infections. Home remedies should be advised like warm water with lemon, steam inhalation for boosting immunity. Plate diet should be advised for Diabetes. Also one should consult a diabetologist for regular monitoring of blood sugar levels. Breathing exercises like yoga are very beneficial for healthy lifestyle.

Carbohydrate counting and Diabetes

Do you know why do we count carbohydrate in Diabetes? Carbohydrate counting is the amount of carbohydrate intake in our body in units which provides energy to the body and also increases the blood sugar levels. It is usually counted to monitor the diet, meal intake to regulate the sugar control.

If you take insulin, carbohydrates counting can help you know how much insulin is needed. Not all people suffering from diabetes need to count carbohydrates. Carbohydrate counting is usually counted in grams. Let us first understand which foods are rich in carbohydrates. Some of the carbohydrate rich foods include milk and milk products, rice, starchy substances, sugars, sweets, fruits, processed foods and juices, refined grains, carbonated aerated drinks. One must avoid such substances or keep control over eating habits of carbohydrates.

carbs counting

If you take insulin during your meal time then one needs to monitor the carbohydrate intake so that it doesn’t increase your sugar levels and also one can judge the amount of insulin required for the body.

Advantages of carbohydrates counting in Diabetes:

  • It helps in improving the lifestyle.
  • Improves your activity and prevents sluggishness.
  • It prevents or delays the complications of Diabetes like Diabetic Nephropathy, Neuropathy, retinopathy, obesity, cardiovascular diseases, hypertension etc.

One carb serving gives 15 grams of carbohydrates. Every body needs different amounts of carbohydrates. If you have 2 baked potatoes, it gives 2 carb servings with total of 30 grams of carbohydrates. Also the amount of carbohydrates needed by the body depends upon various factors like age, weight, activity of the individual etc. A person usually takes 1800 to 1900 calories/day , out of which 900 to 1000 calories consists of carbohydrates as indian’s eat more of carbs. If 4 calories/gram of carb then 225-250 grams of carbs per day. One needs to avoid fried oily fatty foods, starchy substances to control body weight and maintain blood sugar levels. Try to eat same amount of carbohydrates every day to maintain a stable blood sugar level.

Carbohydrate serving 15 grams meal plan:

Starch: 1 slice of bread, 1/4 cup of pasta, 3/4 cup cereals

Milk: one cup of skimmed milk or 3/4 cup curd

Fruit: One small piece of fruit or 1/2 cup of fruit juice

Desert: 2 small buiscuits or  1/2 cup ice cream.

Tools that can be useful to patients as they become familiar with carbohydrate counting include measuring cups and spoons, food package labels, food scales, carbohydrate counting books.

Advanced Carbohydrate Counting:

However the following skills are required for people who have understood basic carbohydrate counting and wish to learn more advanced carbohydrate counting level (e.g., if a patient is planning to use an insulin pump or a bolus insulin regimen).

  • Ability to count all aspects of basic carbohydrate counting.
  • Understanding the concept of target blood glucose levels.
  • Understanding the concept of action of insulin and the basal-bolus insulin.
  • Willingness and ability to keep complete proper records.
  • Willingness to do pattern management.

Additionally one needs to know how to calculate a bolus insulin dose using insulin-to-carbohydrate ratios, insulin sensitivity factor for correction or supplementation of insulin doses when glucose levels are either too high or too low before meals, and how to make corrections for such special situations.

There are various ways and methods for determining insulin-to-carbohydrate ratios. For patients with type 1 diabetes, the general rule is that most people need about half of their total daily dose of insulin for basal insulin and half for their bolus doses to cover their meals. In type 2 diabetes, the basal and bolus demands can vary from patient to patient. Bolus insulin doses is calculated from the insulin-to-carbohydrate ratio which is based on the total grams of carbohydrate or the total number of 15gm carbohydrate servings consumed.

How to determine insulin carbohydrate ratio:

  • First record the total amount of carbohydrate intake during meals and snacks for 3 days. It will vary as per the activity and demand of the person.
  • Note down the blood glucose levels for 3 days.
  • Calculate the average intake of carbohydrates of 3 days and average of blood glucose levels. Then one can determine the amount of insulin required for that average blood glucose levels.
  • Then one can calculate the ratio of insulin carbohydrate ratio by dividing the number of grams of carbohydrate in a meal by number of bolus insulin given in units.

Hope our readers understood the simple way of calculating carbohydrate in your meal and plan your meal accordingly. Also the importance of monitoring carbohydrates in regulating the blood glucose levels and also manage the intake of insulin injections accordingly. One also needs to consult your diabetologist for proper guidance for calculating carbohydrate intake and insulin dose regulation.

Diabetes and Gangrene – Symptoms Types and Treatment

Hello everyone!!! Let us first understand what is gangrene and it’s role in diabetes. Gangrene is a condition whereby there is poor blood circulation to the tissues leading to the death of the cell tissue and necrosis due to lack of blood supply. When the blood glucose levels are increased in the blood, there is poor circulation of blood to the tissues which leads to Gangrene. There are two types of Gangrene namely: Dry and wet gangrene. Gangrene usually occurs in extremities hands , legs, toes, fingers.

Common symptoms of Gangrene are:

  • Degenerative changes in the tissue
  • The affected area becomes brown and then turns black.
  • Pain with numbness of the affected region.

About half of the Indian population is suffering from diabetes and from that one forth of the population suffer from gangrene.

Diabetic foot:

Diabetic foot is a complication of prolonged uncontrolled Diabetes. According to Wagner’s classification, Diabetic foot is graded into five grades:

  •  0- when the skin over the foot is intact
  •  I -superficial ulcer
  •  II -deep ulcer occurs
  • III -osteomyelitis of bone /deep abcess/pus formation
  • IV – front of the foot gangrene
  •  V -heels and back of the foot affected gangrene

Factors that lead to Diabetes Gangrene (causes):

  • Diabetes
  • Smoking
  • Alcohol
  • Obesity
  • Varicose veins
  • Autoimmune diseases
  • Frostbite
  • Trauma/injury

Diabetes and gangrene

Types of Gangrene:

Dry gangrene:

In this type of gangrene, the blood sugar level is high which leads to loss of blood supply to the peripheral tissue. The skin becomes brown first and later on black. There is a lot of pain and numbness of the affected area like foot or hand.

Wet gangrene:

This type of gangrene usually occurs in both type 1 and type 2 Diabetes. This results in blister, pain and swelling of the affected area due to infection. Th affected region becomes black and there is accumulation of pus inside which later oozes out. Along with that, there is itching and pain of that area. Diabetic foot is also called as gangrene. This also results in neuropathy of the affected area resulting in numbness of the region. Wet gangrene is usually bacterial infectious. The affected region is infected by streptococcus or Escheria bacteria or  Clostridius perfrigenous bacteria.

Gas gangrene:

Gas gangrene is a bacterial infection that produces gas within tissues caused by clostridium perfringens and other toxic bacterias. It is accompanied with pain, swelling and gas in the tissue and lot of inflammation.

Necrotising fasciitis (NF) is a deep tissue infection caused by bacteria like Staphylococcus or Streptococcus leading to similar symptoms of wet gangrene.

Noma gangrene:

Here the gangrene refers to the face due to increased blood sugar levels.

Fournier’s gangrene:

This refers to gangrene of the genitals causing pain, swelling and fever. Wet gangrene when worsened can also lead to fever and sepsis. It can also affect the fertility of the patient. Appropriate control measures must be taken for controlling both diabetes and gangeene.

Meleney’s gangrene:

This type is very rare and usually causes painful lesions on your skin within 2 weeks after surgery or minor trauma.

Internal gangrene:

This usually occurs in the internal organs especially appendix and colon. The patient has a lot of pain in right hypochondriac region with vomiting coinciding syptoms of appendicitis. But here there is another indication of increase prolonged diabetes.

Treatment and Management of diabetes and Gangrene:

  • Manage your disease conditions. If you have diabetes, please keep a regular check of blood sugar levels, any kind of slow healing injury andaskin disease etc.
  •  Wounds. Take medical immediately if you see signs of infection.
  • Avoid smoking. As smoking damages the blood vessels.
  • Mantain your weight as per BMI. Extra weight can exert pressure on your arteries thus blocking blood flow.
  • Keep yourself warm. Frostbite also blocks blood flow and the skin becomes pale, numb and can lead to gangrene.

Diagnosis:

Blood test: Get the blood tests done, glucose levels tested both fasting and post pariandal levels. One needs to monitor the glucose levels in the blood every month in case of gangrene. Also blood culture can help conclude the bacteria like steptococus, clostradial infections.

MRI/CT scan of vital organs necessary for ruling out internal Gangrene. Also it determines the extent of spread internally in skin, fascia, tissue etc.

X-ray of foot or hand suggestive of any injury leading to gangrene. Appropriate measures must be taken as per symptomatology.

Treatment of Gangrene and diabetes.

Treatment of gangrene involves removing dead tissue, treating and stopping the spread of infection. Treating the causative condition that caused the gangrene leads to speady recovery.

Treatment usually depends on the type of gangrene and may include:

Surgery. This is also called debridement. Dead tissue is removed to control the sprwsp of infection. This might need to remove an affected limb, finger or to also known as amputation.

Oxygenation of the affected region:

Hyperbaric oxygen therapy can treat  gangrene or ulcers related to diabetes or peripheral artery disease. Patient needs to spend time in a special chamber filled with oxygen at a higher pressure than oxygen found in the outside air. This high level of oxygen fills your blood hemoglobin and speeds tissue healing. It also helps in slowing down the growth of the bacteria.

Treating surgeon will need to find out what’s blocking your blood supply and treat that condition. Like incase of cardiac block one needs to get angioplasty done or in case of vascular disease like varicose veins or DVT one needs to get operated for clearing the blocked blood vessels.

Maggot’s treatment:

This method was practiced in olden days to remove the dead tissue in gangrene. Maggots still do play a good role in modern medicine. Your respective doctor puts maggots from fly larvae (specially bred in laboratory) on your wound, where they eat dead and infected tissue without hurting healthy tissue. They also help fight infection and speed healing by releasing chemicals or so called secretions that kill bacteria.

Antibiotics:

Intravenous or intramuscular antibiotics are given to the patient to control infection and septic conditions in gangrene. Also if the diabetes is high, insulin in monitored dose is injected either subcutaneously or intravenous drip to further control complications.

Hope after reading this article, one needs to understand the importance of monitored sugar in our life!!! Stay safe# Stay healthy!!!

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Top 5 tips for managing obesity in diabetes

A positive association between obesity and risk of T2DM has been established repeatedly in many cross-sectional and prospective studies. The association of obesity with T2DM is complex and compounded by many factors. Obesity not only is a risk factor for development of diabetes, but also complicates the management of the disease.

A person is at high risk for diabetes if he/she is overweight (body mass index [BMI] of 25 kg/m or BMI >23) and have one or more additional risk factors, such as:

  • Less physical activity
  • Family history of T2DM
  • High-risk race/ethnicity (African American, American Indian or Alaska Native, Asian American, Hispanic or Latino, Native Hawaiian or Pacific Islander)
  • High blood pressure (140/90 mmHg or higher)
  • High cholesterol (240 mg/dL or higher)
  • Clinical conditions associated with insulin resistance, such as severe obesity, or the development of dark, thick skin in body folds and creases (a condition which is called “acanthosis nigricans”)
  • History of Cardiovascular Disease (CVD)
  • Have prediabetes

Tips For Management of Obesity in Diabetes-

1] Re-invent the patient’s diet plan :

Processed foods such as white bread, biscuits, cakes, etc. increase the risk of developing diabetes. Hence, their consumption must be avoided. Also the intake of whole grains should be increased, as these foods have complex mixture of components which benefit the
health. Avoid trans-fatty acids, which are commonly found in margarines, fried foods, and many packaged/ processed foods. Instead, include intake of fats from sources such as nuts, avocados, fatty fishes, eggs, etc.

2] Ensure intake of the right nutrients :

Revised diet plan must contain the following:

  • High-quality multivitamins and minerals
  • One to two grams of omega-3 fatty acids
  • 1,000 – 2,000 IUs of vitamin D3
  • 300 – 600 mg of alpha lipoic acid twice daily
  • 200 – 600 mcg of chromium polynicotinate

3] Shedding weight :

apple shape obesity
Image credit: kanakaveda.com

Shedding pounds can improve blood glucose levels and help keep T2DM under control. People who have more abdominal fat (apple shape) have a greater risk of developing T2DM than those with fat mostly in the thighs, hips, and buttocks (pear shape). A healthy diet and regular aerobic exercise helps in shedding as well as maintaining ideal weight.

4] Getting the right exercise :

A person with diabetes does not need to spend hours at a gym to get exercise’s benefits. A simple 30-minute walk everyday can help. It is an effective exercise that helps balance blood sugar glucose and lower insulin levels.

5] Measures to improve health :

Records show that people who track their progress tend to lose twice as much weight, and do twice as well. Ask the patient to begin recording in order to track their own progress. Paper pads, notebooks, spreadsheets in their computer are examples of some tools which may help the same. In addition to what they eat a baseline of all measurements: weight, waist size, BMI, and blood pressure (optional) should be recorded every week. Many patients become inspired when they see their results on paper.

These management strategies can have a dramatic impact on blood glucose levels and the progression of T2DM. Simple lifestyle changes will improve the patient’s quality of life, and will help ensure a healthier future.

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