Charcot foot and Diabetes

Charcot foot is a serious complication with people suffering from diabetes. The patient suffers from peripheral neuropathy along with diabetes. It affects the bones, joints and deeper soft tissues of foot and ankle. The bones become weak and fragile and ankle can easily dislocate. Charcot’s foot is also known as Charcot’s arthropathy. When the midfoot is involved in this, the arch of the foot collapses, which curls around the bottom of the foot. This is known as rocker-bottom foot deformity.

Charcot Foot’s known cause is Diabetic Neuropathy.  Due to foot deformities, there is abnormal pressure on the plantar surface of the foot which lead to foot ulcers. This in turn leads to nerve damage and there is loss of sensation, unilateral swelling and erythema of the foot. When the patient is suffering from diabetes, the foot ulcers pose a high risk for amputation of foot. Hence one needs to be cautious for any injury, frostbite etc. Obesity can also lead to pressure over the foot. There may be slight pain if the sensory loss is not complete. However one can misjudge the diagnosis for cellulitis. The bones of the foot slowly begin to lose calcium which makes the bones strong.

Charcot foot And Diabetes

Charcot Foot Causes:

  • Alcohol/drug abuse
  • Spinal cord injury/disease
  • HIV
  • Parkinson’s disease
  • Any infection
  • Syphilis
  • Injury to foot
  • Sprain to ankle
  • Any foot surgery very slow to heal

There is no specific cause for charcot’s foot. The above mentioned are the trigger factors for this disease.

Diagnosis:

Sometimes charcot’s foot can also mimic deep vein thrombosis. A venous duplex scan can help to rule out venous occlusion. X Ray of affected foot show bony destruction, joint subluxation, fragmentation and bony remodelling.

Charcot Foot Treatment:

Immobilisation of foot:

This protects the feet to move and create pressure. One can use crutches, wheelchair or a knee Walker to go around. One should rest for at least 2 months to avoid unnecessary pressure on the foot. Also offloading the foot, that is putting the foot into cast which protects the foot from bearing weight and helps in immobilisation. This cast is changed several times till the swelling of the foot goes down. Orthopedic footwear usually relieves pressure points and avoids ulcers and injury.

Repair bones with surgery:

Any injury to the foot can make your foot unstable, or you can’t wear special shoes or braces then surgery would help in such cases. Also in cases of sore foot, surgery is necessary.

Care your foot:

Focus on your foot. Make sure you go for regular checkups for diabetes. Look for signs like unilateral swelling, warm spots, redness, sores or ulcers. Check for any redness and sores in-between your toes. Wash your feet daily. Always wear your socks and shoes.

Treatment with antimicrobial medicines:

When the patient has lot of pain and swelling of the foot with accumulation of abscess leading to ulcer, then antimicrobials are the first choice of the physician.

When surgery is the only choice:

Surgery is adviced for those patients who have severe foot and ankle deformities endangering to foot ulcers. Amputation is done when foot ulcer worsens. Also Diabetes should be under complete check.

Complications:

When the patient suffers from deformity of ankle, the joint may become unstable or “floppy” due to replacement of the tissue o er the bone joint. This “floppy foot” can lead to ulcers. Foot ulcers are difficult to heal due to uncontrolled Diabetes, which leads to poor circulation in feet, leading to Infections. This condition can be threatening causing amputation of foot depending upon the extent of infection.

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Diabetes and Gangrene – Symptoms Types and Treatment

Hello everyone!!! Let us first understand what is gangrene and it’s role in diabetes. Gangrene is a condition whereby there is poor blood circulation to the tissues leading to the death of the cell tissue and necrosis due to lack of blood supply. When the blood glucose levels are increased in the blood, there is poor circulation of blood to the tissues which leads to Gangrene. There are two types of Gangrene namely: Dry and wet gangrene. Gangrene usually occurs in extremities hands , legs, toes, fingers.

Common symptoms of Gangrene are:

  • Degenerative changes in the tissue
  • The affected area becomes brown and then turns black.
  • Pain with numbness of the affected region.

About half of the Indian population is suffering from diabetes and from that one forth of the population suffer from gangrene.

Diabetic foot:

Diabetic foot is a complication of prolonged uncontrolled Diabetes. According to Wagner’s classification, Diabetic foot is graded into five grades:

  •  0- when the skin over the foot is intact
  •  I -superficial ulcer
  •  II -deep ulcer occurs
  • III -osteomyelitis of bone /deep abcess/pus formation
  • IV – front of the foot gangrene
  •  V -heels and back of the foot affected gangrene

Factors that lead to Diabetes Gangrene (causes):

  • Diabetes
  • Smoking
  • Alcohol
  • Obesity
  • Varicose veins
  • Autoimmune diseases
  • Frostbite
  • Trauma/injury

Diabetes and gangrene

Types of Gangrene:

Dry gangrene:

In this type of gangrene, the blood sugar level is high which leads to loss of blood supply to the peripheral tissue. The skin becomes brown first and later on black. There is a lot of pain and numbness of the affected area like foot or hand.

Wet gangrene:

This type of gangrene usually occurs in both type 1 and type 2 Diabetes. This results in blister, pain and swelling of the affected area due to infection. Th affected region becomes black and there is accumulation of pus inside which later oozes out. Along with that, there is itching and pain of that area. Diabetic foot is also called as gangrene. This also results in neuropathy of the affected area resulting in numbness of the region. Wet gangrene is usually bacterial infectious. The affected region is infected by streptococcus or Escheria bacteria or  Clostridius perfrigenous bacteria.

Gas gangrene:

Gas gangrene is a bacterial infection that produces gas within tissues caused by clostridium perfringens and other toxic bacterias. It is accompanied with pain, swelling and gas in the tissue and lot of inflammation.

Necrotising fasciitis (NF) is a deep tissue infection caused by bacteria like Staphylococcus or Streptococcus leading to similar symptoms of wet gangrene.

Noma gangrene:

Here the gangrene refers to the face due to increased blood sugar levels.

Fournier’s gangrene:

This refers to gangrene of the genitals causing pain, swelling and fever. Wet gangrene when worsened can also lead to fever and sepsis. It can also affect the fertility of the patient. Appropriate control measures must be taken for controlling both diabetes and gangeene.

Meleney’s gangrene:

This type is very rare and usually causes painful lesions on your skin within 2 weeks after surgery or minor trauma.

Internal gangrene:

This usually occurs in the internal organs especially appendix and colon. The patient has a lot of pain in right hypochondriac region with vomiting coinciding syptoms of appendicitis. But here there is another indication of increase prolonged diabetes.

Treatment and Management of diabetes and Gangrene:

  • Manage your disease conditions. If you have diabetes, please keep a regular check of blood sugar levels, any kind of slow healing injury andaskin disease etc.
  •  Wounds. Take medical immediately if you see signs of infection.
  • Avoid smoking. As smoking damages the blood vessels.
  • Mantain your weight as per BMI. Extra weight can exert pressure on your arteries thus blocking blood flow.
  • Keep yourself warm. Frostbite also blocks blood flow and the skin becomes pale, numb and can lead to gangrene.

Diagnosis:

Blood test: Get the blood tests done, glucose levels tested both fasting and post pariandal levels. One needs to monitor the glucose levels in the blood every month in case of gangrene. Also blood culture can help conclude the bacteria like steptococus, clostradial infections.

MRI/CT scan of vital organs necessary for ruling out internal Gangrene. Also it determines the extent of spread internally in skin, fascia, tissue etc.

X-ray of foot or hand suggestive of any injury leading to gangrene. Appropriate measures must be taken as per symptomatology.

Treatment of Gangrene and diabetes.

Treatment of gangrene involves removing dead tissue, treating and stopping the spread of infection. Treating the causative condition that caused the gangrene leads to speady recovery.

Treatment usually depends on the type of gangrene and may include:

Surgery. This is also called debridement. Dead tissue is removed to control the sprwsp of infection. This might need to remove an affected limb, finger or to also known as amputation.

Oxygenation of the affected region:

Hyperbaric oxygen therapy can treat  gangrene or ulcers related to diabetes or peripheral artery disease. Patient needs to spend time in a special chamber filled with oxygen at a higher pressure than oxygen found in the outside air. This high level of oxygen fills your blood hemoglobin and speeds tissue healing. It also helps in slowing down the growth of the bacteria.

Treating surgeon will need to find out what’s blocking your blood supply and treat that condition. Like incase of cardiac block one needs to get angioplasty done or in case of vascular disease like varicose veins or DVT one needs to get operated for clearing the blocked blood vessels.

Maggot’s treatment:

This method was practiced in olden days to remove the dead tissue in gangrene. Maggots still do play a good role in modern medicine. Your respective doctor puts maggots from fly larvae (specially bred in laboratory) on your wound, where they eat dead and infected tissue without hurting healthy tissue. They also help fight infection and speed healing by releasing chemicals or so called secretions that kill bacteria.

Antibiotics:

Intravenous or intramuscular antibiotics are given to the patient to control infection and septic conditions in gangrene. Also if the diabetes is high, insulin in monitored dose is injected either subcutaneously or intravenous drip to further control complications.

Hope after reading this article, one needs to understand the importance of monitored sugar in our life!!! Stay safe# Stay healthy!!!

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Top 5 tips for managing obesity in diabetes

A positive association between obesity and risk of T2DM has been established repeatedly in many cross-sectional and prospective studies. The association of obesity with T2DM is complex and compounded by many factors. Obesity not only is a risk factor for development of diabetes, but also complicates the management of the disease.

A person is at high risk for diabetes if he/she is overweight (body mass index [BMI] of 25 kg/m or BMI >23) and have one or more additional risk factors, such as:

  • Less physical activity
  • Family history of T2DM
  • High-risk race/ethnicity (African American, American Indian or Alaska Native, Asian American, Hispanic or Latino, Native Hawaiian or Pacific Islander)
  • High blood pressure (140/90 mmHg or higher)
  • High cholesterol (240 mg/dL or higher)
  • Clinical conditions associated with insulin resistance, such as severe obesity, or the development of dark, thick skin in body folds and creases (a condition which is called “acanthosis nigricans”)
  • History of Cardiovascular Disease (CVD)
  • Have prediabetes

Tips For Management of Obesity in Diabetes-

1] Re-invent the patient’s diet plan :

Processed foods such as white bread, biscuits, cakes, etc. increase the risk of developing diabetes. Hence, their consumption must be avoided. Also the intake of whole grains should be increased, as these foods have complex mixture of components which benefit the
health. Avoid trans-fatty acids, which are commonly found in margarines, fried foods, and many packaged/ processed foods. Instead, include intake of fats from sources such as nuts, avocados, fatty fishes, eggs, etc.

2] Ensure intake of the right nutrients :

Revised diet plan must contain the following:

  • High-quality multivitamins and minerals
  • One to two grams of omega-3 fatty acids
  • 1,000 – 2,000 IUs of vitamin D3
  • 300 – 600 mg of alpha lipoic acid twice daily
  • 200 – 600 mcg of chromium polynicotinate

3] Shedding weight :

apple shape obesity
Image credit: kanakaveda.com

Shedding pounds can improve blood glucose levels and help keep T2DM under control. People who have more abdominal fat (apple shape) have a greater risk of developing T2DM than those with fat mostly in the thighs, hips, and buttocks (pear shape). A healthy diet and regular aerobic exercise helps in shedding as well as maintaining ideal weight.

4] Getting the right exercise :

A person with diabetes does not need to spend hours at a gym to get exercise’s benefits. A simple 30-minute walk everyday can help. It is an effective exercise that helps balance blood sugar glucose and lower insulin levels.

5] Measures to improve health :

Records show that people who track their progress tend to lose twice as much weight, and do twice as well. Ask the patient to begin recording in order to track their own progress. Paper pads, notebooks, spreadsheets in their computer are examples of some tools which may help the same. In addition to what they eat a baseline of all measurements: weight, waist size, BMI, and blood pressure (optional) should be recorded every week. Many patients become inspired when they see their results on paper.

These management strategies can have a dramatic impact on blood glucose levels and the progression of T2DM. Simple lifestyle changes will improve the patient’s quality of life, and will help ensure a healthier future.

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Link Between Hypothyroidism and PCOS

Hypothyroidism and PCOS linked.

Did you know that hypothyroidism and PCOD (Polycystic Ovarian Disorder) are interconnected?. Both the diseases are more commonly found in young girls and women. Hypothyroidism is known to cause PCOS and worsening of PCOD with insulin resistance. An increased estrogenic and estrogenic/progesterone ratio seem to be directly involved in high thyroid antibody levels in PCOS patients. Both the diseases are linked with each other. Hypothyroidism can lead to Polycystic ovarian disease. Both hypothyroidism and PCOD are seen most commonly in teen girls.

hypothyroidism hashimotos and pcos

Pathophysiology:

Factors contributing PCOD and hypothyroidism in young girls and women are obesity, junk food, carbonated aerated drinks, sedentary life-style, hormonal changes which tend to affect the ovaries causing development of cysts. Both environmental and genetic factors lead to contribute to thyroid disorders in PCOD. Also, family history of hypothyroidism cannot be ruled out as one of the causes. High prolactin levels affects in LH/FSH ratio which leads to decrease in thyrotoxin T4 levels and increase in TSH levels leading to PCOD.

PCOD also leads to increase insulin resistance and may cause infertility in young women. There is irregular menstrual cycle leading to amenorrhea. Ovulation is disturbed with pain in the lower abdomen. Best way to diagnose is ultrasonography of pelvis during the fourth or fifth day of menstrual cycle. Multiple follicular cysts are seen in the ovaries along with increase in size of the ovaries in ultrasonography. Elevated free testosterone level is an indicator for increase androsterone hormone for PCOD.

Hypothyroidism symptoms may overlap PCOD like amenorrhoea, hairfall, weight gain, hirsutism and infertility. Apart from this, hypothyroidism also includes symptoms like headaches, constipation, lethargy, muscle cramps, sluggishness, sexual dysfunction, brittle nails and bradycardia. Also glycaemic index, and thyroid levels would give clear idea of to rule out hypothyroidism.

Obesity :

Obesity caused by Hypothyroidism can be treated by improving the lifestyle. Implementation of exercise and a proper diet plan can help in reducing weight which is also useful in treatment of PCOD. Also treatment with oral eltroxin or L-Thyroxine helps in Hypothyroidism.

Hypothyroidism, PCOS and pregnancy :

All these are also interlinked which can lead to obesity, hypertension, lethargy, hairfall and headaches. Alteration in thyroid hormones also affects the brain development (IQ) of the baby. Also eating lower glycemic foods also help in monitoring diabetes and PCOD.  Reducing stress levels and correcting sleeping patterns help in correcting Hypothyroidism, PCOD.

Also patients suffering from PCOD do have subclinical hypothyroidism  where in TSH levels increases in PCOD patients.

Home remedies for hypothyroidism and PCOD:

  • Licoriceroot in herbal tea is very useful for Hypothyroidism. It reduces androgen which helps in restoring the hormonal balance.
  • Having fenugreek seeds (methi seeds) empty stomach in the morning helps in both Hypothyroidism and PCOD.
  • Corriander and mint juice also helps in easing painful menstrual cycle in PCOD.
  • Asafoetida local application over stomach helps in pain during menstrual cycle in PCOD. Also drinking buttermilk with asafoetida helps.
  • Avoiding cabbage, capsicum, cauliflower in large quantities helps in controlling hypothyroidism as they trap iodine from blood stream.

All the above mentioned home remedies and diet would help you achieve your goals. Hope you all gained some knowledge about the importance and how both the diseases ie Hypothyroidism and PCOD are linked and how to manage through home remedies and medicicine.

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For more details about Hypothyroidsm and PCOS correlation checkout the article in Indian Journal of endocrinology and Metabolism.